Glutamine Modulates Macrophage Lipotoxicity
نویسندگان
چکیده
منابع مشابه
Glutamine Modulates Macrophage Lipotoxicity
Obesity and diabetes are associated with excessive inflammation and impaired wound healing. Increasing evidence suggests that macrophage dysfunction is responsible for these inflammatory defects. In the setting of excess nutrients, particularly dietary saturated fatty acids (SFAs), activated macrophages develop lysosome dysfunction, which triggers activation of the NLRP3 inflammasome and cell d...
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ژورنال
عنوان ژورنال: Nutrients
سال: 2016
ISSN: 2072-6643
DOI: 10.3390/nu8040215